​​​في إطار النشاط العلمي والبحثي لقسم الأحياء بكلية العلوم، أقام القسم ندوة علمية (سمنار علمي) بعنوان:

The impact of Nitric Oxide to induced Lipid Body Formation (LB) in Mycobacterium tuberculosis CDC1551: Roles of tgs1 and lipY

قدّمتها سعادة الدكتوره شيخه بنت عبدالله الباتلي، الأستاذ المساعد في القسم، وذلك يوم الاثنين 23 ربيع أول 1447هـ، الموافق 15 سبتمبر 2025م في تمام الساعة 08:25 صباحاً بقاعة السمنارات في قسم الأحياء  بالكلية.

وقد تناولت الندوة العلمية مايلي:

Tuberculosis (TB) is an infectious disease that is recognized as one of the world's oldest known human diseases and caused by the bacterial pathogen Mycobacterium tuberculosis (M.tb ). The first discovered was by Robert Koch in 1882. Globally in 2020, the number of deaths officially classified as caused by TB  was almost double the number caused by HIV/AIDS, and TB mortality has been more impacted by the COVID-19 pandemic which resulted in reduced access to diagnosis and treatment. Mycobacterial species are non-motile, aerobic, rod-shaped acid-fast bacilli and are closely related to Gram positive bacteria, cell envelope with a high lipid content. There are approximately 120 species in the genus Mycobacterium, which is naturally divided into two groups: Slow growers, such as Mtb and Fast growers, such as M smegmatis.  The structure of the cell wall involves many unique lipids and glycolipids, a deficiency of which has been associated with increased cell wall permeability and other phenotypes. Mtb resistance to environmental stress, antibiotics, is due in part to the low permeability of its cell wall. Macrophages can accumulate lipid droplets in response to Mtb infection. M.tb can access these lipids and accumulate LBs. Following phagocytosis, the infection is commonly stopped by the bactericidal activities of activate​d macrophages, such as lysosomal enzymes. However, once inside the macrophage, Mtb has several survival mechanisms that allow it to persist in the host. It is possible to manip​ulate the LB content of Mtb CDC1551 with NO/OA and that this is related to the induction of DosR regulon.

كما استعرضت الدكتوره أبرز المحاور والنتائج ذات الصلة، مقدمتاً طرحاً علمياً قيّماً أثار نقاشاً مثمراً بين أعضاء هيئة التدريس والطالبات الحاضرات. 

وتأتي هذه الندوة ضمن سلسلة الأنشطة العلمية التي يحرص قسم الأحياء على تنظيمها بشكل دوري وذلك في إطار تعزيز النشاط البحثي والأكاديمي بالقسم وحرصاً على إتاحة الفرصة للتفاعل العلمي وتبادل الخبرات والمعارف بين أعضاء هيئة التدريس والباحثين وطلاب الدراسات العليا بالقسم.

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